Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23860161 | 0.90 | ALDH1A1 (0.44) | STAT3CYP2D6CYP1A2ALDH1A1KMT2A | |
| SCHEMBL2389377 | 0.87 | ALDH1A1 (0.45) | STAT3CYP2D6CYP1A2ALDH1A1KMT2A | |
| SCHEMBL23705651 | 0.86 | STAT3 (0.44) | STAT3CYP2D6CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL4828186 | 0.84 | GPR119 (0.47) | KMT2AMEN1 | |
| SCHEMBL16414751 | 0.83 | STAT3 (0.41) | STAT3CYP2D6CYP1A2PSMD10ALDH1A1 | |
| SCHEMBL30058693 | 0.82 | KMT2A (0.43) | ALDH1A1KMT2APOLBMEN1LMNA | |
| SCHEMBL16415252 | 0.81 | STAT3 (0.39) | STAT3CYP2D6CYP1A2PSMD10ALDH1A1 | |
| SCHEMBL25389881 | 0.81 | STAT3 (0.44) | STAT3CYP2D6CYP1A2ALDH1A1HSD17B10 | |
| SCHEMBL23089207 | 0.80 | STAT3 (0.38) | STAT3CYP2D6CYP1A2PSMD10ALDH1A1 | |
| SCHEMBL23540983 | 0.80 | STAT3 (0.39) | STAT3CYP2D6CYP1A2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4097096-A2 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |
| WO-2019118612-A1 | TARGETING COMPOUNDS | ZAFGEN, INC. (US) | 2019-06-20 | — | — | WO | disclosed |