Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | CTSC | P53634 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.41 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.41 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.41 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2727898 | 1.00 | SLC7A5 (0.47) | SLC7A5CYP3A4SLC1A3HSD17B10PKM | |
| SCHEMBL2727900 | 1.00 | SLC7A5 (0.47) | SLC7A5CYP3A4SLC1A3HSD17B10PKM | |
| SCHEMBL3659943 | 0.75 | PARP15 (0.44) | CTSCPARP15PARP10SLC6A3TDP1 | |
| SCHEMBL6193383 | 0.74 | PARP15 (0.36) | CTSCPARP15PARP10SLC6A3TDP1 | |
| SCHEMBL6193388 | 0.74 | PARP15 (0.36) | CTSCPARP15PARP10SLC6A3TDP1 | |
| SCHEMBL9480 | 0.74 | PARP15 (0.43) | PARP15PARP10SLC6A3TDP1LMNA | |
| SCHEMBL16160203 | 0.74 | CHRM1 (0.41) | CYP3A4HSD17B10CTSC | |
| SCHEMBL9727913 | 0.73 | SLC6A3 (0.38) | CTSCPARP15PARP10SLC6A3 | |
| SCHEMBL6652600 | 0.73 | SLC6A3 (0.38) | PARP15PARP10SLC6A3TDP1LMNA | |
| SCHEMBL6652598 | 0.73 | SLC6A3 (0.38) | CTSCPARP15PARP10SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10329321-B2 | Site-selective functionalization of proteins using traceless affinity labels | Krantz, Alexander (US) | 2019-06-25 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10329321-B2 | Site-selective functionalization of proteins using traceless affinity labels | MYCBP, FABP3, STUB1 | SLC7A5 955/4885CYP3A4 3090/4885SLC1A3 677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.