SCHEMBL21065475

SCHEMBL21065475

C=Cc1c(F)c(F)c(OS(=O)(=O)CCC)c(F)c1F.[NaH]

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
MMP2 P08253 1/20 0.30
MMP7 P09237 1/20 0.30
MMP9 P14780 1/20 0.30
MMP14 P50281 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1401601 0.85 CA2 (0.46) CA1CA2CA9MMP2MMP7
SCHEMBL1401780 0.71 CA1 (0.52) CA1CA2CA9
SCHEMBL7154139 0.67 CA1 (0.43) CA1CA2CA9
SCHEMBL16466661 0.66 HSD17B10 (0.32)
SCHEMBL12620756 0.66 CA1 (0.46) CA1CA2CA9
SCHEMBL15449281 0.66 HTT (0.33)
SCHEMBL27853475 0.65
SCHEMBL15449278 0.65
SCHEMBL29209233 0.65 ALPL (0.35) CA2MMP2MMP7MMP9MMP14
SCHEMBL7604250 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3501050-A1 METHOD FOR PREPARING PARTICLES SUITABLE FOR CATALYSING OXYGEN REDUCTION OR HYDROGEN OXIDATION, THE PARTICLES BEING PROTON-CONDUCTING BY GRAFTING SPECIFIC PROTON-CONDUCTING FLUORINATED POLYMERS TO THE SURFACE THEREOF Commissariat à l'Énergie Atomique et aux Énergies Alternatives (FR) 2019-06-26 EP disclosed