SCHEMBL21065621

SCHEMBL21065621

CCCOC(F)(C(C)=O)C(F)(F)F

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.33
ALDH1A1 P00352 2/20 0.32
LMNA P02545 1/20 0.31
FAAH O00519 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1784672 0.83 LMNA (0.34) CES2ALDH1A1LMNAFAAH
SCHEMBL236895 0.83 CES2 (0.33) CES2ALDH1A1LMNAFAAH
SCHEMBL10340016 0.81 CES2 (0.32) CES2ALDH1A1
SCHEMBL2269852 0.81 CES2 (0.32) CES2ALDH1A1
Fluoride SCHEMBL9617438 0.81 LMNA (0.33) CES2ALDH1A1LMNA
Hydrochloric Acid SCHEMBL10522738 0.81 LMNA (0.33) CES2ALDH1A1LMNA
SCHEMBL10319993 0.81 CES2 (0.36) CES2ALDH1A1FAAH
Ammonia Solution, Strong SCHEMBL1580153 0.81 LMNA (0.33) CES2ALDH1A1LMNA
Potassium Ion SCHEMBL11656858 0.79 CES2 (0.32) CES2
Fluoride SCHEMBL27286213 0.79 CES2 (0.32) CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3727686-A1 MOISTURE-CURING COMPOSITIONS Covestro Deutschland AG (DE) 2020-10-28 EP claimed
EP-3501641-A1 MOISTURE-CURABLE COMPOSITIONS Covestro Deutschland AG (DE) 2019-06-26 EP claimed
EP-3727686-A1 MOISTURE-CURING COMPOSITIONS Covestro Deutschland AG (DE) 2020-10-28 EP disclosed
EP-3501641-A1 MOISTURE-CURABLE COMPOSITIONS Covestro Deutschland AG (DE) 2019-06-26 EP disclosed
CN-108276555-A Glass lens polymerizable composition, polymerizable composition and the manufacturing method for using its glass lens SKC株式会社 2018-07-13 CN disclosed