⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6144719 | 0.73 | LMNA (0.34) | — | |
| SCHEMBL4999817 | 0.72 | LMNA (0.33) | — | |
| SCHEMBL10402922 | 0.71 | — | — | |
| SCHEMBL30502381 | 0.70 | LMNA (0.32) | — | |
| SCHEMBL22551437 | 0.70 | LMNA (0.32) | — | |
| SCHEMBL2242675 | 0.70 | LMNA (0.32) | — | |
| SCHEMBL30502380 | 0.70 | LMNA (0.32) | — | |
| SCHEMBL2244551 | 0.70 | SLC6A2 (0.32) | — | |
| SCHEMBL21630244 | 0.69 | GRIN1 (0.32) | — | |
| SCHEMBL8992710 | 0.69 | LMNA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3727686-B1 | MOISTURE-CURABLE COMPOSITIONS | COVESTRO INTELLECTUAL PROPERTY GMBH & CO KG (DE) | 2023-05-10 | — | — | EP | disclosed |
| EP-3501641-A1 | MOISTURE-CURABLE COMPOSITIONS | Covestro Deutschland AG (DE) | 2019-06-26 | — | — | EP | disclosed |