Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | ACR | P10323 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9256020 | 0.87 | KMT2A (0.45) | KMT2AMAPTLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL18744675 | 0.86 | MAPT (0.54) | KMT2AMAPTGFERLMNASMN1; SMN2 | |
| SCHEMBL12869645 | 0.84 | MAPT (0.64) | KMT2AMAPTLMNASMN1; SMN2CA1 | |
| SCHEMBL5089928 | 0.84 | MAPT (0.55) | KMT2AMAPTGFERLMNASMN1; SMN2 | |
| SCHEMBL7868900 | 0.84 | MAPT (0.55) | KMT2AMAPTGFERLMNASMN1; SMN2 | |
| SCHEMBL7776960 | 0.84 | MAPT (0.55) | KMT2AMAPTGFERLMNASMN1; SMN2 | |
| SCHEMBL1069709 | 0.82 | LMNA (0.48) | MAPTLMNACA1CA2KDM4E | |
| SCHEMBL1069708 | 0.82 | LMNA (0.48) | MAPTLMNACA1CA2KDM4E | |
| SCHEMBL12633724 | 0.80 | LMNA (0.75) | KMT2AMAPTGFERLMNASMN1; SMN2 | |
| SCHEMBL7591660 | 0.80 | LMNA (0.75) | KMT2AMAPTGFERLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3500890-A1 | COMPOSITE FILM, DEVICE INCLUDING, AND METHOD OF FORMING THE SAME | Nanyang Technological University (SG) | 2019-06-26 | — | — | EP | disclosed |