Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.31 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CHKA | P35790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18136192 | 0.82 | KDM4E (0.45) | HTT | |
| SCHEMBL21230341 | 0.81 | CA2 (0.37) | QRFPRTRPV4CA2CHKA | |
| SCHEMBL19974425 | 0.81 | QRFPR (0.33) | HTTQRFPRTRPV4CA2CHKA | |
| SCHEMBL19974053 | 0.81 | QRFPR (0.33) | QRFPRTRPV4CA2CHKA | |
| SCHEMBL29538895 | 0.81 | QRFPR (0.33) | HTTQRFPRTRPV4CA2CHKA | |
| SCHEMBL25888568 | 0.79 | CNR2 (0.35) | QRFPRTRPV4 | |
| SCHEMBL21698353 | 0.78 | MCHR1 (0.34) | QRFPR | |
| SCHEMBL20100075 | 0.78 | S1PR1 (0.36) | QRFPR | |
| SCHEMBL22436278 | 0.77 | — | — | |
| SCHEMBL22030440 | 0.76 | HCRTR2 (0.32) | QRFPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3500568-A1 | METHOD FOR PRODUCING 2-(3,6-DIHALOPYRIDIN-2-YL)-3H-IMIDAZOL[4,5-C]PYRIDINE DERIVATIVES AND RELATED COMPOUNDS BY REACTION OF THE 3H-IMIDAZOL[4,5-C]PYRIDINE DERIVATIVE WITH AN ORGANOMETALLIC ZINC-AMINE BASE | Bayer CropScience Aktiengesellschaft (DE) | 2019-06-26 | — | — | EP | disclosed |