Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.31 |
| ▸ | CDK9 | P50750 | 1/20 | 0.31 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.30 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 2/20 | 0.30 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19712049 | 0.88 | S1PR1 (0.35) | S1PR1CYP2D6MAP3K12QRFPR | |
| SCHEMBL19712050 | 0.88 | S1PR1 (0.35) | S1PR1CYP2D6MAP3K12QRFPR | |
| SCHEMBL22931309 | 0.88 | CCNT1 (0.30) | CCNT1CDK9 | |
| SCHEMBL21698390 | 0.86 | S1PR1 (0.40) | S1PR1CYP3A4CYP2C19MAP3K12QRFPR | |
| SCHEMBL21698427 | 0.86 | S1PR1 (0.40) | S1PR1CYP3A4CYP2C19MAP3K12QRFPR | |
| SCHEMBL18136192 | 0.80 | KDM4E (0.45) | CYP3A4TSHR | |
| SCHEMBL21065788 | 0.78 | ALOX15 (0.32) | QRFPR | |
| SCHEMBL19974425 | 0.78 | QRFPR (0.33) | QRFPR | |
| SCHEMBL21230341 | 0.78 | CA2 (0.37) | QRFPR | |
| SCHEMBL29538895 | 0.78 | QRFPR (0.33) | QRFPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3356362-B1 | 2-(HET)ARYL-SUBSTITUTED CONDENSED HETEROCYCLIC DERIVATIVES USEFUL AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-02-03 | — | — | EP | disclosed |
| US-10745398-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-08-18 | — | — | US | disclosed |
| EP-3280716-B1 | IMIDAZO[1,2-A]PYRIDIN-2-YL DERIVATIVES AS PESTICIDES AND INTERMEDIATES THEREOF | BAYER CROPSCIENCE AG (DE) | 2020-02-12 | — | — | EP | disclosed |
| US-10375962-B2 | Heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-08-13 | — | — | US | disclosed |
| US-10188108-B2 | Fused bicyclic heterocycle derivatives as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-01-29 | — | — | US | disclosed |
| US-20190021329-A1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-01-24 | — | — | US | disclosed |
| US-20180116222-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | US | disclosed |
| US-20180116222-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10375962-B2 | Heterocycle derivatives as pesticides | DDT, ACHE, CBR1 | S1PR1 2044/4885CYP3A4 277/4885CYP2D6 1136/4885 |
| US-10745398-B2 | 2-(het)aryl-substituted fused heterocycle derivatives as pesticides | CYP4X1, CYP1A1, CYP8B1 | S1PR1 2525/4885CYP3A4 25/4885CYP2D6 102/4885 |
| US-10188108-B2 | Fused bicyclic heterocycle derivatives as pesticides | DDT, CBR3, CYCS | S1PR1 2273/4885CYP3A4 78/4885CYP2D6 470/4885 |
| US-20180116222-A1 | FUSED BICYCLIC HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, CBR3, CYCS | S1PR1 2273/4885CYP3A4 78/4885CYP2D6 470/4885 |
| US-20190021329-A1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, ACHE, CBR1 | S1PR1 2044/4885CYP3A4 277/4885CYP2D6 1136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.