Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | PKM | P14618 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1321714 | 0.78 | NPSR1 (0.47) | MAPTLMNAKDM4ETSHRALDH1A1 | |
| SCHEMBL28945418 | 0.76 | TSHR (0.46) | MAPTLMNAKDM4ETSHRALDH1A1 | |
| SCHEMBL28945449 | 0.76 | ALDH1A1 (0.57) | MAPTLMNAKDM4ETSHRALDH1A1 | |
| SCHEMBL6923839 | 0.76 | MAPT (0.41) | MAPTLMNAKDM4ETSHRALDH1A1 | |
| SCHEMBL4960868 | 0.76 | MAPT (0.41) | MAPTLMNAKDM4ETSHRALDH1A1 | |
| SCHEMBL22463559 | 0.72 | ALDH1A1 (0.51) | MAPTKDM4ETSHRALDH1A1NPSR1 | |
| SCHEMBL14896375 | 0.70 | NPSR1 (0.47) | MAPTLMNAKDM4ETSHRALDH1A1 | |
| SCHEMBL11947641 | 0.69 | DPP4 (0.48) | MAPTLMNATSHRALDH1A1NPSR1 | |
| SCHEMBL28786392 | 0.68 | CYP1A2 (0.41) | LMNAKDM4EALDH1A1NPSR1HTT | |
| Hydrochloric Acid SCHEMBL7464122 | 0.68 | DPP4 (0.47) | MAPTLMNATSHRALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3501546-A2 | CYSTEINE DRUG CONJUGATES AND USE OF SAME | Seattle Genetics, Inc. (US) | 2019-06-26 | — | — | EP | disclosed |