Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4958071 | 0.83 | CYP19A1 (0.51) | NPSR1NPC1SMN1; SMN2CYP1A2CYP2D6 | |
| SCHEMBL4957486 | 0.83 | CYP1A2 (0.51) | LMNAKDM4ENPSR1SMN1; SMN2CYP1A2 | |
| SCHEMBL4958557 | 0.81 | TNF (0.44) | MAPTLMNAKDM4EKMT2ANPSR1 | |
| SCHEMBL4959914 | 0.80 | SLC6A2 (0.40) | MAPTLMNANPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL4960149 | 0.79 | SMN1; SMN2 (0.42) | NPSR1SMN1; SMN2CYP1A2CYP2D6PKM | |
| SCHEMBL4959314 | 0.78 | SLC6A2 (0.37) | NPSR1SMN1; SMN2CYP1A2CYP2D6PKM | |
| SCHEMBL6923839 | 0.77 | MAPT (0.41) | MAPTLMNAKDM4EKMT2ANPSR1 | |
| SCHEMBL4959372 | 0.77 | TNF (0.46) | LMNAKDM4EALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL4958049 | 0.77 | SLC6A2 (0.57) | NPSR1SMN1; SMN2CYP1A2CYP2D6PKM | |
| SCHEMBL21065965 | 0.76 | MAPT (0.44) | MAPTLMNAKDM4EKMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879873-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK Holdings Co., Ltd. (KR) | 2008-01-23 | — | — | EP | disclosed |
| WO-2006112685-A1 | NEUROTHERAPEUTIC AZOLE COMPOUNDS | SK HOLDINGS CO., LTD. (KR) | 2006-10-26 | — | — | WO | disclosed |