Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 13/20 | 0.66 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.66 |
| ▸ | HTR2C | P28335 | 2/20 | 0.61 |
| ▸ | HTR2A | P28223 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | MAOB | P27338 | 8/20 | 0.56 |
| ▸ | MAOA | P21397 | 7/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.56 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11668623 | 0.81 | HTR2A (0.50) | KDM1AHDAC6HTR2CHTR2AHTR2B | |
| SCHEMBL526938 | 0.80 | KDM1A (1.00) | KDM1AHDAC6MAOBMAOACYP2C9 | |
| SCHEMBL29352901 | 0.80 | KDM1A (1.00) | KDM1AHDAC6MAOBMAOACYP2C9 | |
| SCHEMBL6837351 | 0.80 | KDM1A (1.00) | KDM1AHDAC6MAOBMAOACYP2C9 | |
| SCHEMBL17512879 | 0.80 | KDM1A (1.00) | KDM1AHDAC6MAOBMAOACYP2C9 | |
| SCHEMBL526937 | 0.80 | KDM1A (1.00) | KDM1AHDAC6MAOBMAOACYP2C9 | |
| SCHEMBL15783273 | 0.80 | KDM1A (1.00) | KDM1AHDAC6MAOBMAOACYP2C9 | |
| SCHEMBL23923444 | 0.79 | HTR2A (0.56) | KDM1AHDAC6HTR2CHTR2AHTR2B | |
| SCHEMBL23940041 | 0.79 | HTR2A (0.56) | KDM1AHDAC6HTR2CHTR2AHTR2B | |
| SCHEMBL23923443 | 0.79 | HTR2A (0.56) | KDM1AHDAC6HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190194179-A1 | ANTIBIOTIC COMPOUNDS | DISCUVA LTD. (GB) | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194179-A1 | ANTIBIOTIC COMPOUNDS | B3GNT2, RPN2, RPN1 | KDM1A 3825/4885HDAC6 391/4885HTR2C 4391/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.