Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 10/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | IKBKE | Q14164 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29941589 | 1.00 | TBK1 (0.65) | TBK1KMT2AMEN1LMNAKDM4E | |
| SCHEMBL19196792 | 0.79 | TBK1 (1.00) | TBK1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL7678962 | 0.77 | MEN1 (0.59) | KMT2AMEN1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL23752331 | 0.76 | KMT2A (0.63) | TBK1KMT2AMEN1KDM4ESMN1; SMN2 | |
| SCHEMBL19204192 | 0.72 | TBK1 (0.71) | TBK1KDM4ENPC1RAB9AIKBKE | |
| SCHEMBL2371734 | 0.71 | TBK1 (0.54) | TBK1KMT2AMEN1LMNAKDM4E | |
| SCHEMBL5780089 | 0.69 | MAOA (0.67) | TBK1KMT2AMEN1LMNAKDM4E | |
| SCHEMBL20317288 | 0.69 | KMT2A (0.48) | KMT2AMEN1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL20317291 | 0.69 | KMT2A (0.48) | KMT2AMEN1LMNAKDM4ESMN1; SMN2 | |
| SCHEMBL20346665 | 0.69 | MEN1 (0.48) | KMT2AMEN1LMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |