Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 13/20 | 1.00 |
| ▸ | HSP90AB1 | P08238 | 13/20 | 1.00 |
| ▸ | HTR7 | P34969 | 7/20 | 0.66 |
| ▸ | HTR2B | P41595 | 6/20 | 0.58 |
| ▸ | HTR1A | P08908 | 5/20 | 0.58 |
| ▸ | HTR6 | P50406 | 5/20 | 0.58 |
| ▸ | HTR3A | P46098 | 4/20 | 0.58 |
| ▸ | HTR2A | P28223 | 2/20 | 0.58 |
| ▸ | HTR5A | P47898 | 2/20 | 0.58 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21067834 | 0.76 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1 | |
| SCHEMBL4474252 | 0.74 | HSP90AA1 (0.59) | HSP90AA1HSP90AB1HTR3A | |
| SCHEMBL3803829 | 0.70 | HTR7 (0.59) | HSP90AA1HSP90AB1HTR7HTR2BHTR1A | |
| SCHEMBL4483461 | 0.69 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1 | |
| SCHEMBL4930499 | 0.68 | HSP90AA1 (0.51) | HSP90AA1HSP90AB1HTR7HTR1AHTR3A | |
| SCHEMBL4483335 | 0.68 | HSP90AA1 (1.00) | HSP90AA1HSP90AB1 | |
| SCHEMBL2738997 | 0.67 | ADRB1 (0.71) | HSP90AA1HSP90AB1HTR7HTR2BHTR1A | |
| SCHEMBL23216866 | 0.67 | ADRB1 (0.53) | HSP90AA1HSP90AB1HTR7HTR2BHTR1A | |
| Hydrochloric Acid SCHEMBL2767700 | 0.66 | ADRB1 (0.69) | HSP90AA1HSP90AB1HTR7HTR2BHTR1A | |
| SCHEMBL14081025 | 0.65 | POLB (0.76) | HTR7HTR2BHTR1AHTR6HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |