Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.47 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | OGT | O15294 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4281610 | 0.84 | EGFR (0.54) | NAMPTMAPK8MAPK10EGFRFGFR1 | |
| SCHEMBL28655500 | 0.81 | NTRK1 (0.50) | KDM1AMAOAMAOBITGB1ITGA2 | |
| SCHEMBL15813925 | 0.79 | NAMPT (0.43) | NAMPTKDM1AMAOAMAOBKMT2A | |
| SCHEMBL20729411 | 0.78 | KCNH3 (0.41) | NAMPTKDM1AMAOAMAOBMAPK8 | |
| SCHEMBL24720685 | 0.77 | OGT (0.44) | NAMPTKDM1AMAOAMAOBKMT2A | |
| SCHEMBL4966121 | 0.77 | HPGD (0.45) | NAMPTKMT2APOLBMAPK8MAPK10 | |
| SCHEMBL23507791 | 0.76 | KDM1A (0.44) | NAMPTKDM1AMAOAMAOBKMT2A | |
| SCHEMBL15815784 | 0.75 | NAMPT (0.43) | NAMPTKDM1AMAOAMAOBPOLB | |
| SCHEMBL7807810 | 0.74 | NAMPT (0.70) | NAMPTKDM1AMAOAMAOBKMT2A | |
| SCHEMBL22831669 | 0.74 | MAPT (0.45) | KMT2AMEN1GAAOGTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |