SCHEMBL4966121

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2691909	0.87	EGFR (0.45)	IRAK4RIPK2CYP2A6EGFRFGFR1
	SCHEMBL4281610	0.85	EGFR (0.54)	HTTMAPTGAAEGFRFGFR1
	SCHEMBL4973242	0.85	NPC1 (0.51)	MAPTIRAK4RIPK2CYP2A6ROCK2
	SCHEMBL2732987	0.85	HTT (0.50)	HTTIRAK4RIPK2ALDH1A1ROCK2
	SCHEMBL4966637	0.83	LMNA (0.60)	KMT2AMAPTALDH1A1ROCK2ROCK1
	SCHEMBL28668115	0.82	LMNA (0.49)	HPGDKMT2AMAPTRIPK2ALDH1A1
	SCHEMBL4968277	0.82	NAMPT (0.61)	MAPTGAAALDH1A1ROCK2ROCK1
	SCHEMBL2689818	0.82	NAMPT (0.54)	HTTIRAK4RIPK2ROCK2ROCK1
	SCHEMBL14904622	0.81	RXFP1 (0.40)	HPGDHTTIRAK4RIPK2ROCK2
	SCHEMBL2689806	0.80	CYP2A6 (0.49)	HTTIRAK4GAARIPK2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.