Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GALR3 | O60755 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13627978 | 1.00 | MAPK8 (0.40) | MAPK8CHRM5HCRTR1HCRTR2TRPA1 | |
| SCHEMBL13627961 | 0.92 | MAPK8 (0.40) | MAPK8CHRM5HCRTR1HCRTR2NPC1 | |
| SCHEMBL13628317 | 0.91 | MAPK8 (0.38) | MAPK8HCRTR1HCRTR2NPC1RAB9A | |
| SCHEMBL13628226 | 0.91 | MAPK8 (0.40) | MAPK8CHRM5HCRTR1HCRTR2NPC1 | |
| SCHEMBL13628213 | 0.91 | UCHL1 (0.40) | MAPK8HCRTR1HCRTR2NPC1RAB9A | |
| SCHEMBL14269960 | 0.91 | UCHL3 (0.43) | MAPK8HCRTR1HCRTR2NPC1RAB9A | |
| SCHEMBL14269986 | 0.91 | POLB (0.39) | MAPK8HCRTR1HCRTR2NPC1RAB9A | |
| SCHEMBL13628284 | 0.90 | MAPK8 (0.38) | MAPK8CHRM5HCRTR1HCRTR2TRPA1 | |
| SCHEMBL13198007 | 0.89 | NPC1 (0.40) | MAPK8CHRM5HCRTR1HCRTR2TRPA1 | |
| SCHEMBL13628324 | 0.89 | TSHR (0.39) | MAPK8CHRM5HCRTR1HCRTR2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |