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SCHEMBL21067350

SCHEMBL21067350

CSCCC(N)C(=O)NS(=O)(=O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MARS1 P56192 6/20 1.00
▸ SARS1 P49591 1/20 0.80
▸ LARS1 Q9P2J5 1/20 0.79
▸ TARS1 P26639 2/20 0.76
▸ RARS1 P54136 1/20 0.75
▸ IARS1 P41252 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL178826 1.00 MARS1 (1.00) MARS1SARS1LARS1TARS1RARS1
SCHEMBL178820 1.00 MARS1 (1.00) MARS1SARS1LARS1TARS1RARS1
SCHEMBL4308351 1.00 MARS1 (1.00) MARS1SARS1LARS1TARS1RARS1
SCHEMBL13773210 0.91 MARS1 (0.84) MARS1SARS1LARS1TARS1RARS1
SCHEMBL13773209 0.91 MARS1 (0.84) MARS1SARS1LARS1TARS1RARS1
SCHEMBL13773211 0.91 MARS1 (0.84) MARS1SARS1LARS1TARS1RARS1
SCHEMBL13773213 0.90 MARS1 (0.82) MARS1SARS1LARS1TARS1RARS1
SCHEMBL13773214 0.90 MARS1 (0.82) MARS1SARS1LARS1TARS1RARS1
SCHEMBL13773212 0.90 MARS1 (0.82) MARS1SARS1LARS1TARS1RARS1
SCHEMBL5063189 0.89 SARS1 (0.82) MARS1SARS1LARS1TARS1RARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11446398-B2 Regulated biocircuit systems OBSIDIAN THERAPEUTICS, INC. (US) 2022-09-20 — — US disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 — — US disclosed