Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SARS1 | P49591 | 1/20 | 0.82 |
| ▸ | MARS1 | P56192 | 1/20 | 0.80 |
| ▸ | RARS1 | P54136 | 1/20 | 0.80 |
| ▸ | LARS1 | Q9P2J5 | 2/20 | 0.79 |
| ▸ | QARS1 | P47897 | 1/20 | 0.78 |
| ▸ | TARS1 | P26639 | 2/20 | 0.76 |
| ▸ | IARS1 | P41252 | 1/20 | 0.73 |
| ▸ | HARS1 | P12081 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5063184 | 1.00 | SARS1 (0.82) | SARS1MARS1RARS1LARS1QARS1 | |
| SCHEMBL3500697 | 0.94 | SARS1 (0.82) | SARS1MARS1RARS1LARS1TARS1 | |
| SCHEMBL178823 | 0.92 | SARS1 (0.85) | SARS1MARS1RARS1LARS1TARS1 | |
| SCHEMBL178824 | 0.92 | SARS1 (0.85) | SARS1MARS1RARS1LARS1TARS1 | |
| SCHEMBL13773209 | 0.91 | MARS1 (0.84) | SARS1MARS1RARS1LARS1TARS1 | |
| SCHEMBL13773211 | 0.91 | MARS1 (0.84) | SARS1MARS1RARS1LARS1TARS1 | |
| SCHEMBL13773210 | 0.91 | MARS1 (0.84) | SARS1MARS1RARS1LARS1TARS1 | |
| SCHEMBL21068060 | 0.90 | SARS1 (0.87) | SARS1MARS1RARS1LARS1TARS1 | |
| SCHEMBL21067959 | 0.90 | SARS1 (1.00) | SARS1MARS1RARS1LARS1TARS1 | |
| SCHEMBL3187665 | 0.90 | SARS1 (0.87) | SARS1MARS1RARS1LARS1TARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080318884-A1 | Methods for Altering Gene Expression and Methods of Treatment Utilizing Same | THE UAB RESEARCH FOUNDATION (US) | 2008-12-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080318884-A1 | Methods for Altering Gene Expression and Methods of Treatment Utilizing Same | TRDMT1, TARBP1, TRMT1 | SARS1 24/4885MARS1 111/4885RARS1 26/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.