Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 10/20 | 1.00 |
| ▸ | GSK3B | P49841 | 6/20 | 1.00 |
| ▸ | MEN1 | O00255 | 7/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.57 |
| ▸ | POLB | P06746 | 6/20 | 0.57 |
| ▸ | BLM | P54132 | 1/20 | 0.57 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.57 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.57 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | G6PD | P11413 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23752472 | 0.73 | GSK3B (1.00) | CDK2GSK3BMEN1KMT2APOLB | |
| SCHEMBL26054607 | 0.67 | KDM4E (0.54) | CDK2GSK3BMEN1KMT2APOLB | |
| SCHEMBL5188402 | 0.65 | CDK2 (0.48) | CDK2GSK3BMEN1KMT2APOLB | |
| SCHEMBL5189038 | 0.65 | CDK2 (0.48) | CDK2GSK3BMEN1KMT2APOLB | |
| SCHEMBL5143187 | 0.64 | CDK2 (0.47) | CDK2GSK3BMEN1KMT2APOLB | |
| SCHEMBL3758734 | 0.64 | CDK2 (0.47) | CDK2GSK3BMEN1KMT2APOLB | |
| SCHEMBL18891690 | 0.63 | ALDH1A1 (0.60) | GSK3BMEN1KMT2APOLBG6PD | |
| SCHEMBL3364834 | 0.63 | MEN1 (1.00) | CDK2GSK3BMEN1KMT2APOLB | |
| SCHEMBL12990149 | 0.63 | MEN1 (1.00) | CDK2GSK3BMEN1KMT2APOLB | |
| SCHEMBL3364832 | 0.63 | MEN1 (1.00) | CDK2GSK3BMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4256086-A1 | METHODS AND SYSTEMS OF STRATIFYING INFLAMMATORY DISEASE PATIENTS | Cedars-Sinai Medical Center (US) | 2023-10-11 | — | — | EP | disclosed |
| EP-4162076-A1 | TREATMENTS FOR A SUB-POPULATION OF INFLAMMATORY BOWEL DISEASE PATIENTS | Cedars-Sinai Medical Center (US) | 2023-04-12 | — | — | EP | disclosed |
| WO-2022119842-A1 | METHODS AND SYSTEMS OF STRATIFYING INFLAMMATORY DISEASE PATIENTS | CEDARS-SINAI MEDICAL CENTER (US) | 2022-06-09 | — | — | WO | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |