SCHEMBL21067571

SCHEMBL21067571

N[C@H](CCc1ccccc1)P(=O)(O)C[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 15/20 1.00
ERAP1 Q9NZ08 14/20 1.00
ERAP2 Q6P179 13/20 1.00
LAP3 P28838 4/20 1.00
ENPEP Q07075 1/20 0.88
IL1RN P18510 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21067570 1.00 ANPEP (1.00) ANPEPERAP1ERAP2LAP3ENPEP
SCHEMBL9646484 0.82 ERAP1 (0.70) ANPEPERAP1ERAP2LAP3ENPEP
SCHEMBL9696151 0.81 ANPEP (0.72) ANPEPERAP1ERAP2LAP3ENPEP
SCHEMBL29371424 0.79 ERAP2 (1.00) ANPEPERAP1ERAP2LAP3IL1RN
SCHEMBL9697346 0.79 ERAP1 (0.65) ANPEPERAP1ERAP2LAP3ENPEP
SCHEMBL10958332 0.78 ERAP1 (0.68) ANPEPERAP1ERAP2LAP3ENPEP
SCHEMBL9647855 0.77 ERAP2 (0.63) ANPEPERAP1ERAP2LAP3ENPEP
SCHEMBL5059848 0.77 FOLH1 (0.69) ANPEPERAP1ERAP2LAP3
SCHEMBL1859177 0.77 CYP1A2 (0.73) ANPEPERAP1ERAP2LAP3
SCHEMBL6518228 0.75 ANPEP (1.00) ANPEPERAP1ERAP2LAP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed