Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 10/20 | 0.72 |
| ▸ | ERAP2 | Q6P179 | 9/20 | 0.72 |
| ▸ | ERAP1 | Q9NZ08 | 7/20 | 0.68 |
| ▸ | LAP3 | P28838 | 4/20 | 0.68 |
| ▸ | MME | P08473 | 1/20 | 0.64 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24991322 | 0.92 | ANPEP (0.76) | ANPEPERAP2ERAP1LAP3MME | |
| Bromide SCHEMBL1764739 | 0.90 | ANPEP (0.74) | ANPEPERAP2ERAP1LAP3MME | |
| SCHEMBL1764058 | 0.87 | ANPEP (0.57) | ANPEPERAP2ERAP1LAP3MME | |
| SCHEMBL5916348 | 0.86 | ENPEP (0.58) | ANPEPERAP2ERAP1LAP3MME | |
| SCHEMBL9697346 | 0.85 | ERAP1 (0.65) | ANPEPERAP2ERAP1LAP3ENPEP | |
| Hydrochloric Acid SCHEMBL5916347 | 0.85 | ENPEP (0.57) | ANPEPERAP2ERAP1LAP3MME | |
| SCHEMBL1780381 | 0.84 | MME (0.73) | ANPEPMME | |
| SCHEMBL6927389 | 0.84 | MME (0.73) | ANPEPMME | |
| SCHEMBL23752212 | 0.84 | MME (0.73) | ANPEPMME | |
| Hydrochloric Acid SCHEMBL5916398 | 0.84 | ENPEP (0.65) | ANPEPERAP2MMEENPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143908-A | Carboxylic acids containing amino and phosphinyl groups | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| US-5099063-A | 3-(1-aminoalkylphosphinyl)-(2-substituted)propionic acids | MERCK & CO., INC. (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0266978-A2 | Novel antibacterial agents and potentiators of carbapenem antibiotics | MERCK & CO. INC. (US) | 1988-05-11 | — | — | EP | disclosed |
| US-4715994-A | PHOSPHINIC ACID DERIVATIVES | MERCK & CO., INC. (US) | 1987-12-29 | — | — | US | disclosed |