Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMS | P04818 | 11/20 | 0.55 |
| ▸ | DHFR | P00374 | 2/20 | 0.47 |
| ▸ | FOLR2 | P14207 | 1/20 | 0.47 |
| ▸ | FOLR1 | P15328 | 1/20 | 0.47 |
| ▸ | GART | P22102 | 1/20 | 0.47 |
| ▸ | ATIC | P31939 | 1/20 | 0.47 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.47 |
| ▸ | SLC19A1 | P41440 | 1/20 | 0.47 |
| ▸ | FRK | P42685 | 1/20 | 0.47 |
| ▸ | SLC46A1 | Q96NT5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19929242 | 0.84 | TYMS (0.51) | TYMSDHFRFOLR2FOLR1GART | |
| SCHEMBL21161374 | 0.79 | TYMS (0.49) | TYMSDHFR | |
| SCHEMBL166747 | 0.79 | TYMS (0.49) | TYMSDHFR | |
| SCHEMBL7163242 | 0.79 | TYMS (0.67) | TYMSDHFR | |
| SCHEMBL20883318 | 0.79 | TYMS (0.45) | TYMSDHFRFOLR2FOLR1GART | |
| SCHEMBL21187099 | 0.78 | TYMS (0.46) | TYMSDHFRFOLR2FOLR1GART | |
| Hydrochloric Acid SCHEMBL29602465 | 0.78 | TYMS (0.48) | TYMSDHFR | |
| SCHEMBL19929245 | 0.77 | PNP (0.48) | TYMS | |
| SCHEMBL24231638 | 0.76 | TYMS (0.52) | TYMSDHFRFOLR2FOLR1GART | |
| SCHEMBL19929106 | 0.76 | PNP (0.51) | TYMSDHFRFOLR2FOLR1GART |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |