SCHEMBL19929245

SCHEMBL19929245

CCCNCc1c[nH]c2nc(N)[nH]c(=O)c12

nearest known ligand 0.57

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PNP P00491 1/20 0.48
TYMS P04818 7/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17662614 0.92 PNP (0.46) PNPTYMS
Hydrochloric Acid SCHEMBL19253833 0.91 PNP (0.46) PNPTYMS
Hydrochloric Acid SCHEMBL19328559 0.91 PNP (0.46) PNPTYMS
SCHEMBL17652055 0.90 PNP (0.45) PNPTYMS
Hydrochloric Acid SCHEMBL19253840 0.89 PNP (0.44) PNPTYMS
SCHEMBL21161374 0.84 TYMS (0.49) TYMS
SCHEMBL14453489 0.83 TYMS (0.47) TYMS
SCHEMBL29094260 0.81 TYMS (0.50) PNPTYMS
SCHEMBL19929241 0.80 PNP (0.48) PNPTYMS
SCHEMBL26250293 0.80 TYMS (0.47) PNPTYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11684611-B2 Compounds for treating diseases associated with a mitochondrial dysfunction AMABIOTICS (FR) 2023-06-27 US disclosed
US-11684611-B2 Compounds for treating diseases associated with a mitochondrial dysfunction AMABIOTICS (FR) 2023-06-27 US disclosed
US-11684611-B2 Compounds for treating diseases associated with a mitochondrial dysfunction AMABIOTICS (FR) 2023-06-27 US disclosed
CN-110035758-B Compounds for the treatment of diseases associated with mitochondrial dysfunction AMA生物制药公司 2023-06-16 CN disclosed
US-20230040247-A1 COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES AMABIOTICS (FR) 2023-02-09 US disclosed
US-20230040247-A1 COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES AMABIOTICS (FR) 2023-02-09 US disclosed
EP-4028014-A1 COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES Stellate Therapeutics (FR) 2022-07-20 EP disclosed
WO-2021048430-A1 COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES AMABIOTICS (FR) 2021-03-18 WO disclosed
WO-2021048430-A1 COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES AMABIOTICS (FR) 2021-03-18 WO disclosed
WO-2021048431-A1 COMPOUNDS FOR TREATING ATAXIA AMABIOTICS (FR) 2021-03-18 WO disclosed
US-20210052589-A1 COMPOUNDS FOR TREATING ALZHEIMER'S DISEASE AMABIOTICS (FR) 2021-02-25 US disclosed
US-20210052589-A1 COMPOUNDS FOR TREATING ALZHEIMER'S DISEASE AMABIOTICS (FR) 2021-02-25 US disclosed
US-20210046056-A1 Compounds for Treating Diseases Associated with a Mitochondrial Dysfunction AMABIOTICS (FR) 2021-02-18 US disclosed
US-20210046056-A1 Compounds for Treating Diseases Associated with a Mitochondrial Dysfunction AMABIOTICS (FR) 2021-02-18 US disclosed
US-10857135-B2 Compounds for treating diseases associated with a mitochondrial dysfunction AMABIOTICS (FR) 2020-12-08 US disclosed
US-10857135-B2 Compounds for treating diseases associated with a mitochondrial dysfunction AMABIOTICS (FR) 2020-12-08 US disclosed
WO-2019170834-A1 COMPOUNDS FOR TREATING ALZHEIMER'S DISEASE AMABIOTICS (FR) 2019-09-12 WO disclosed
US-20190224174-A1 COMPOUNDS FOR TREATING DISEASES ASSOCIATED WITH A MITOCHONDRIAL DYSFUNCTION AMABIOTICS (FR) 2019-07-25 US disclosed
US-20190224174-A1 COMPOUNDS FOR TREATING DISEASES ASSOCIATED WITH A MITOCHONDRIAL DYSFUNCTION AMABIOTICS (FR) 2019-07-25 US disclosed
WO-2018041919-A1 COMPOUNDS FOR TREATING DISEASES ASSOCIATED WITH A MITOCHONDRIAL DYSFONCTION AMABIOTICS (FR) 2018-03-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230040247-A1 COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES SNCA, HTT, PARK7 PNP 3067/4885TYMS 4634/4885
US-20210046056-A1 Compounds for Treating Diseases Associated with a Mitochondrial Dysfunction NDUFAB1, FH, TFAM PNP 2691/4885TYMS 3412/4885
US-20190224174-A1 COMPOUNDS FOR TREATING DISEASES ASSOCIATED WITH A MITOCHONDRIAL DYSFUNCTION NDUFAB1, FH, TFAM PNP 2691/4885TYMS 3412/4885
US-10857135-B2 Compounds for treating diseases associated with a mitochondrial dysfunction NDUFAB1, FH, TFAM PNP 2691/4885TYMS 3412/4885
US-20210052589-A1 COMPOUNDS FOR TREATING ALZHEIMER'S DISEASE PSEN1, PSEN2, MAPT PNP 3884/4885TYMS 3657/4885
US-11684611-B2 Compounds for treating diseases associated with a mitochondrial dysfunction NDUFAB1, FH, TFAM PNP 2691/4885TYMS 3412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.