SCHEMBL166747

SCHEMBL166747

NCc1c[nH]c2nc(N)[nH]c(=O)c12

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TYMS P04818 9/20 0.49
DHFR P00374 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29602465 0.98 TYMS (0.48) TYMSDHFR
SCHEMBL21161374 0.87 TYMS (0.49) TYMSDHFR
SCHEMBL14453489 0.83 TYMS (0.47) TYMSDHFR
SCHEMBL21067593 0.79 TYMS (0.55) TYMSDHFR
SCHEMBL22967337 0.78 TYMS (0.59) TYMSDHFR
SCHEMBL19929245 0.78 PNP (0.48) TYMS
SCHEMBL18520454 0.77 DYRK1A (0.47) TYMS
SCHEMBL19929242 0.77 TYMS (0.51) TYMSDHFR
SCHEMBL21187099 0.77 TYMS (0.46) TYMSDHFR
SCHEMBL17662614 0.76 PNP (0.46) TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 886 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12559745-B2 Methods and compositions for linking RNA stem loops THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-02-24 US claimed
US-12473573-B2 Switchable Cas9 nucleases and uses thereof PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2025-11-18 US claimed
EP-4600362-A1 REPORTER GENE CONSTRUCT SENSITIVE TO QUEUOSINE LEVELS Instituto Nacional de Técnica Aeroespacial "Esteban Terradas" (ES) 2025-08-13 EP claimed
WO-2025075256-A1 APPARATUS AND METHOD FOR EARLY DISEASE DETECTION BASED ON HIGH-DEPTH CELL-FREE NUCLEIC ACID SEQUENCING (주)지놈포미 2025-04-10 WO claimed
CN-119563035-A Method for screening compounds 德皮克萨斯股份有限公司 2025-03-04 CN claimed
US-20250019719-A1 Purification and Purity Assessment of RNA Molecules Synthesized with Modified Nucleosides THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA 2025-01-16 US claimed
US-20240417780-A1 DETECTION OF NUCLEIC ACID AND NON-NUCLEIC ACID TARGET MOLECULES VEDABIO, INC. 2024-12-19 US claimed
US-12117442-B2 Methods of screening compounds Depixus SAS (FR) 2024-10-15 US claimed
US-12091707-B2 Detection of nucleic acid and non-nucleic acid target molecules VEDABIO, INC. (US) 2024-09-17 US claimed
EP-4426720-A1 MODIFIED MRNA THERAPEUTICS Shattuck Labs, Inc. (US) 2024-09-11 EP claimed
CN-116985675-A External discharge control method and device and automobile 赛力斯汽车有限公司 2023-11-03 CN claimed
EP-4217490-A2 PRIME EDITING GUIDE RNAS, COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME The Broad Institute Inc. (US) 2023-08-02 EP claimed
WO-2023077156-A1 MODIFIED MRNA THERAPEUTICS SHATTUCK LABS, INC. (US) 2023-05-04 WO claimed
WO-2022251242-A1 COMPOSITIONS AND METHODS FOR MODIFYING DNA THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-12-01 WO claimed
CN-113555910-B Energy microgrid system with intelligent hydroelectric energy storage equipment 江苏大学 2022-06-21 CN claimed
CN-113022344-B Power battery charging system based on double motors and electric automobile 重庆长安新能源汽车科技有限公司 2022-05-31 CN claimed
WO-2022109495-A1 METHODS AND COMPOSITIONS FOR LINKING RNA STEM LOOPS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-05-27 WO claimed
US-20220145308-A1 MATERIALS AND METHODS FOR REDUCING NUCLEIC ACID DEGRADATION IN BACTERIA NATIONAL INSTITUTES OF HEALTH 2022-05-12 US claimed
WO-2022067130-A2 PRIME EDITING GUIDE RNAS, COMPOSITIONS THEREOF, AND METHODS OF USING THE SAME THE BROAD INSTITUTE, INC. (US) 2022-03-31 WO claimed
US-11267842-B2 Enzymatic modification of nucleic acids THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-03-08 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11267842-B2 Enzymatic modification of nucleic acids RNGTT, UNG, RNASEL TYMS 172/4885DHFR 251/4885
US-12559745-B2 Methods and compositions for linking RNA stem loops TRDMT1, NSUN3, TRMT1L TYMS 51/4885DHFR 1223/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.