Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 1.00 |
| ▸ | DPP8 | Q6V1X1 | 11/20 | 1.00 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21067975 | 1.00 | DPP4 (1.00) | DPP4DPP8DPP7KCNH2 | |
| Hydrochloric Acid SCHEMBL4160735 | 0.99 | DPP4 (0.98) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL8264882 | 0.86 | DPP4 (0.75) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL1394444 | 0.84 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| SCHEMBL21067640 | 0.84 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| SCHEMBL1846959 | 0.84 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| Hydrochloric Acid SCHEMBL5043367 | 0.83 | DPP4 (0.98) | DPP4DPP8DPP7 | |
| SCHEMBL14440604 | 0.83 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| SCHEMBL14278852 | 0.83 | DPP4 (0.77) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL5132150 | 0.83 | DPP4 (0.77) | DPP4DPP8DPP7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090124601-A1 | Tartaric Acid Salts of a Dipeptidyl Peptidase-IV Inhibitor | MERCK & CO., INC. | 2009-05-14 | — | — | US | claimed |
| WO-2006104997-A2 | TARTARIC ACID SALTS OF A DIPEPTIDYL PEPTIDASE-IV INHIBITOR | MERCK & CO., INC. (US) | 2006-10-05 | — | — | WO | claimed |
| EP-3145915-B1 | ANTIDIABETIC TRICYCLIC COMPOUNDS | MERCK SHARP & DOHME LLC (US) | 2025-03-19 | — | — | EP | disclosed |
| EP-3974413-A1 | ANTIDIABETIC SUBSTITUTED HETEROARYL COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2022-03-30 | — | — | EP | disclosed |
| EP-3082786-B1 | ANTIDIABETIC SUBSTITUTED HETEROARYL COMPOUNDS | MERCK SHARP & DOHME (US) | 2021-10-27 | — | — | EP | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| EP-2906542-B1 | SUBSTITUTED SPIROPIPERIDINYL COMPOUNDS USEFUL AS GPR120 AGONISTS | MERCK SHARP & DOHME (US) | 2019-08-07 | — | — | EP | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |
| US-10000454-B2 | Antidiabetic tricyclic compounds | MERCK SHARP & DOHME (US) | 2018-06-19 | — | — | US | disclosed |
| EP-2780337-B1 | SUBSTITUTED CYCLOPROPYL COMPOUNDS USEFUL AS GPR119 AGONISTS | MERCK SHARP & DOHME (US) | 2017-12-20 | — | — | EP | disclosed |
| EP-2464228-B1 | SUBSTITUTED CYCLOPROPYL COMPOUNDS, COMPOSITIONS CONTAINING SUCH COMPOUNDS AND METHODS OF TREATMENT | MERCK SHARP & DOHME (US) | 2017-12-06 | — | — | EP | disclosed |
| US-20090124601-A1 | Tartaric Acid Salts of a Dipeptidyl Peptidase-IV Inhibitor | MERCK & CO., INC. | 2009-05-14 | — | — | US | disclosed |
| US-20090124601-A1 | Tartaric Acid Salts of a Dipeptidyl Peptidase-IV Inhibitor | MERCK & CO., INC. | 2009-05-14 | — | — | US | disclosed |
| US-20090124601-A1 | Tartaric Acid Salts of a Dipeptidyl Peptidase-IV Inhibitor | MERCK & CO., INC. | 2009-05-14 | — | — | US | disclosed |
| US-20090124601-A1 | Tartaric Acid Salts of a Dipeptidyl Peptidase-IV Inhibitor | MERCK & CO., INC. | 2009-05-14 | — | — | US | disclosed |
| EP-1556362-B1 | BETA-AMINO HETEROCYCLIC DIPEPTIDYL PEPTIDASE INHIBITORS FOR THE TREATMENT OR PREVENTION OF DIABETES | MERCK & CO INC (US) | 2008-03-26 | — | — | EP | disclosed |
| WO-2006104997-A3 | TARTARIC ACID SALTS OF A DIPEPTIDYL PEPTIDASE-IV INHIBITOR | MERCK & CO INC (US) | 2006-12-21 | — | — | WO | disclosed |
| WO-2006104997-A2 | TARTARIC ACID SALTS OF A DIPEPTIDYL PEPTIDASE-IV INHIBITOR | MERCK & CO., INC. (US) | 2006-10-05 | — | — | WO | disclosed |
| WO-2006104997-A2 | TARTARIC ACID SALTS OF A DIPEPTIDYL PEPTIDASE-IV INHIBITOR | MERCK & CO., INC. (US) | 2006-10-05 | — | — | WO | disclosed |
| WO-2006104997-A2 | TARTARIC ACID SALTS OF A DIPEPTIDYL PEPTIDASE-IV INHIBITOR | MERCK & CO., INC. (US) | 2006-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10000454-B2 | Antidiabetic tricyclic compounds | GPR119, GPR65, GPR52 | DPP4 54/4885DPP8 150/4885DPP7 122/4885 |
| US-20090124601-A1 | Tartaric Acid Salts of a Dipeptidyl Peptidase-IV Inhibitor | DPP4, DPP3, DPP7 | DPP4 1/4885DPP8 5/4885DPP7 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.