Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 1.00 |
| ▸ | DPP8 | Q6V1X1 | 11/20 | 1.00 |
| ▸ | DPP7 | Q9UHL4 | 10/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL388929 | 1.00 | DPP4 (1.00) | DPP4DPP8DPP7KCNH2 | |
| Hydrochloric Acid SCHEMBL4160735 | 0.99 | DPP4 (0.98) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL8264882 | 0.86 | DPP4 (0.75) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL1394444 | 0.84 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| SCHEMBL21067640 | 0.84 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| SCHEMBL1846959 | 0.84 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| Hydrochloric Acid SCHEMBL5043367 | 0.83 | DPP4 (0.98) | DPP4DPP8DPP7 | |
| SCHEMBL14440604 | 0.83 | DPP4 (1.00) | DPP4DPP8DPP7 | |
| SCHEMBL14278852 | 0.83 | DPP4 (0.77) | DPP4DPP8DPP7KCNH2 | |
| SCHEMBL5132150 | 0.83 | DPP4 (0.77) | DPP4DPP8DPP7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| EP-2906542-B1 | SUBSTITUTED SPIROPIPERIDINYL COMPOUNDS USEFUL AS GPR120 AGONISTS | MERCK SHARP & DOHME (US) | 2019-08-07 | — | — | EP | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |