SCHEMBL21067658

SCHEMBL21067658

CN(C)C/C=C\c1cc(F)ccc1S(=O)(=O)Nc1ccc2c(c1C(=O)O)CCCC2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
METAP2 P50579 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1314674 0.92 METAP2 (1.00) METAP2
SCHEMBL1314677 0.92 METAP2 (1.00) METAP2
SCHEMBL3984183 0.81 METAP2 (0.71) METAP2
SCHEMBL3988764 0.80 METAP2 (0.70) METAP2
SCHEMBL3986691 0.80 METAP2 (1.00) METAP2
SCHEMBL3986694 0.80 METAP2 (1.00) METAP2
SCHEMBL3988213 0.80 METAP2 (1.00) METAP2
SCHEMBL3981263 0.80 METAP2 (0.69) METAP2
SCHEMBL16176014 0.78 METAP2 (1.00) METAP2
SCHEMBL3979227 0.76 METAP2 (1.00) METAP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed