Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 10/20 | 1.00 |
| ▸ | CA2 | P00918 | 10/20 | 1.00 |
| ▸ | CA9 | Q16790 | 6/20 | 1.00 |
| ▸ | CA12 | O43570 | 4/20 | 1.00 |
| ▸ | CA7 | P43166 | 4/20 | 1.00 |
| ▸ | CA6 | P23280 | 3/20 | 1.00 |
| ▸ | CA5A | P35218 | 3/20 | 1.00 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 1.00 |
| ▸ | CA3 | P07451 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28259515 | 0.76 | CA2 (0.61) | CA1CA2CA9CA12CA7 | |
| SCHEMBL28257304 | 0.75 | CA2 (0.59) | CA1CA2CA9CA12CA7 | |
| SCHEMBL30314797 | 0.74 | KDM4E (1.00) | CA1CA2CA9CA12CA7 | |
| SCHEMBL30314798 | 0.74 | KDM4E (1.00) | CA1CA2CA9CA12CA7 | |
| SCHEMBL11326692 | 0.74 | KDM4E (1.00) | CA1CA2CA9CA12CA7 | |
| SCHEMBL9848132 | 0.73 | ALDH1A1 (0.67) | CA1CA2CA9CA12CA7 | |
| SCHEMBL2439298 | 0.70 | ALDH1A1 (0.62) | CA1CA2CA9CA12CA7 | |
| SCHEMBL21065048 | 0.70 | ALDH1A1 (0.62) | CA1CA2CA9CA12CA7 | |
| SCHEMBL31328400 | 0.70 | ALDH1A1 (0.62) | CA1CA2CA9CA12CA7 | |
| SCHEMBL970693 | 0.70 | ALDH1A1 (0.62) | CA1CA2CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |