Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 18/20 | 0.72 |
| ▸ | HDAC3 | O15379 | 17/20 | 0.72 |
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.72 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15580255 | 0.84 | HDAC3 (1.00) | HDAC1HDAC3HDAC6HDAC8HDAC2 | |
| SCHEMBL29827523 | 0.75 | HDAC1 (0.52) | HDAC1HDAC3HDAC6HDAC8 | |
| SCHEMBL19114550 | 0.75 | HDAC1 (0.69) | HDAC1HDAC3HDAC6HDAC8HDAC2 | |
| SCHEMBL19114280 | 0.74 | HDAC1 (0.74) | HDAC1HDAC3HDAC6HDAC8HDAC2 | |
| SCHEMBL21663724 | 0.72 | HDAC1 (0.49) | HDAC1HDAC3HDAC6HDAC8 | |
| SCHEMBL21663988 | 0.72 | HDAC1 (0.49) | HDAC1HDAC3HDAC6HDAC8 | |
| SCHEMBL15580281 | 0.71 | HDAC1 (0.53) | HDAC1HDAC3HDAC6HDAC8HPGDS | |
| SCHEMBL19114239 | 0.70 | HDAC1 (0.53) | HDAC1HDAC3HDAC6HDAC8HPGDS | |
| SCHEMBL15580223 | 0.69 | HDAC3 (1.00) | HDAC1HDAC3HDAC6HDAC8HDAC2 | |
| SCHEMBL15580301 | 0.68 | HDAC1 (0.71) | HDAC1HDAC3HDAC6HDAC8HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |