Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 17/20 | 1.00 |
| ▸ | HPGD | P15428 | 3/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.71 |
| ▸ | MEN1 | O00255 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | MAPT | P10636 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.71 |
| ▸ | NPC1 | O15118 | 1/20 | 0.70 |
| ▸ | CASP1 | P29466 | 1/20 | 0.70 |
| ▸ | CASP7 | P55210 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23752237 | 0.85 | KIF11 (1.00) | KIF11HPGDHSD17B10MEN1POLB | |
| SCHEMBL3918724 | 0.83 | HPGD (1.00) | KIF11HPGDHSD17B10MAPK1TDP1 | |
| SCHEMBL3914843 | 0.82 | HPGD (0.98) | KIF11HPGDHSD17B10MAPK1TDP1 | |
| SCHEMBL16210883 | 0.79 | KIF11 (0.98) | KIF11HPGDHSD17B10MAPK1TDP1 | |
| SCHEMBL4150336 | 0.78 | SMN1; SMN2 (0.71) | KIF11HPGDHSD17B10MAPK1TDP1 | |
| SCHEMBL12443131 | 0.77 | TP53 (0.80) | KIF11HPGDHSD17B10MAPK1MEN1 | |
| SCHEMBL14156267 | 0.69 | MEN1 (0.60) | KIF11HPGDHSD17B10MAPK1TDP1 | |
| SCHEMBL3921416 | 0.69 | MEN1 (1.00) | KIF11HPGDHSD17B10MEN1LMNA | |
| SCHEMBL6938391 | 0.69 | USP2 (0.69) | KIF11HPGDHSD17B10MEN1LMNA | |
| SCHEMBL3922433 | 0.68 | MEN1 (0.82) | KIF11HPGDHSD17B10MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |