Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 5/20 | 0.73 |
| ▸ | CDK9 | P50750 | 13/20 | 0.65 |
| ▸ | CCNT1 | O60563 | 12/20 | 0.65 |
| ▸ | CDK4 | P11802 | 5/20 | 0.65 |
| ▸ | CCND1 | P24385 | 5/20 | 0.65 |
| ▸ | CDK7 | P50613 | 4/20 | 0.65 |
| ▸ | CCNH | P51946 | 3/20 | 0.65 |
| ▸ | CDK2 | P24941 | 7/20 | 0.62 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.59 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.59 |
| ▸ | GSK3B | P49841 | 1/20 | 0.59 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.59 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.59 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.58 |
| ▸ | FLT3 | P36888 | 1/20 | 0.58 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.56 |
| ▸ | CDK3 | Q00526 | 2/20 | 0.56 |
| ▸ | CDK13 | Q14004 | 2/20 | 0.53 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.53 |
| ▸ | CCNK | O75909 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21946521 | 0.79 | CCNT1 (1.00) | CDK9CCNT1CDK4CCND1CDK7 | |
| Hydrochloric Acid SCHEMBL21877788 | 0.78 | CCNT1 (0.98) | CDK9CCNT1CDK4CCND1CDK7 | |
| SCHEMBL21946129 | 0.77 | CDK9 (0.72) | MAPKAPK2CDK9CCNT1CDK4CCND1 | |
| Hydrochloric Acid SCHEMBL21877609 | 0.76 | CDK9 (0.70) | MAPKAPK2CDK9CCNT1CDK4CCND1 | |
| SCHEMBL23752480 | 0.76 | CDK2 (1.00) | MAPKAPK2CDK2GSK3B | |
| SCHEMBL21946404 | 0.75 | CDK9 (0.88) | MAPKAPK2CDK9CCNT1CDK4CCND1 | |
| SCHEMBL24174222 | 0.75 | CDK9 (0.73) | MAPKAPK2CDK9CCNT1CDK4CCND1 | |
| SCHEMBL21946121 | 0.75 | CDK9 (0.73) | MAPKAPK2CDK9CCNT1CDK4CCND1 | |
| SCHEMBL21946489 | 0.75 | CDK9 (0.65) | MAPKAPK2CDK9CCNT1CDK4CCND1 | |
| SCHEMBL3890298 | 0.75 | MAPKAPK2 (0.80) | MAPKAPK2CDK9CCNT1CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240034799-A1 | METHODS AND SYSTEMS OF STRATIFYING INFLAMMATORY DISEASE PATIENTS | CEDARS SINAI MEDICAL CENTER (US) | 2024-02-01 | — | — | US | disclosed |
| US-20230279491-A1 | TREATMENTS FOR A SUB-POPULATION OF INFLAMMATORY BOWEL DISEASE PATIENTS | CEDARS-SINAI MEDICAL CENTER | 2023-09-07 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |