Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 4/20 | 1.00 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.61 |
| ▸ | GSK3B | P49841 | 1/20 | 0.61 |
| ▸ | CSNK2A2 | P19784 | 16/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21946126 | 0.77 | CCNT1 (0.72) | CDK2GSK3BCSNK2A1 | |
| SCHEMBL14427569 | 0.76 | CDK2 (1.00) | CDK2MAPKAPK2GSK3BCSNK2A2 | |
| SCHEMBL21068045 | 0.76 | MAPKAPK2 (0.73) | CDK2MAPKAPK2GSK3B | |
| SCHEMBL21067605 | 0.74 | CDK2 (1.00) | CDK2CSNK2A2CSNK2A1 | |
| SCHEMBL26867735 | 0.72 | CCNT1 (0.56) | CDK2MAPKAPK2GSK3BCSNK2A2CSNK2A1 | |
| SCHEMBL15288758 | 0.69 | CDK2 (0.64) | CDK2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL26871380 | 0.67 | CSNK2A1 (0.52) | CDK2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL29355477 | 0.67 | KDM4E (0.62) | CDK2CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL33377999 | 0.66 | CSNK2B (0.60) | CDK2GSK3BCSNK2B | |
| SCHEMBL19742468 | 0.66 | CSNK2A2 (0.57) | CDK2GSK3BCSNK2A2CSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4256086-A1 | METHODS AND SYSTEMS OF STRATIFYING INFLAMMATORY DISEASE PATIENTS | Cedars-Sinai Medical Center (US) | 2023-10-11 | — | — | EP | disclosed |
| US-20230279491-A1 | TREATMENTS FOR A SUB-POPULATION OF INFLAMMATORY BOWEL DISEASE PATIENTS | CEDARS-SINAI MEDICAL CENTER | 2023-09-07 | — | — | US | disclosed |
| EP-4162076-A1 | TREATMENTS FOR A SUB-POPULATION OF INFLAMMATORY BOWEL DISEASE PATIENTS | Cedars-Sinai Medical Center (US) | 2023-04-12 | — | — | EP | disclosed |
| WO-2022119842-A1 | METHODS AND SYSTEMS OF STRATIFYING INFLAMMATORY DISEASE PATIENTS | CEDARS-SINAI MEDICAL CENTER (US) | 2022-06-09 | — | — | WO | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |