Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRB2 | P62993 | 1/20 | 0.71 |
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.61 |
| ▸ | ALPI | P09923 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | XIAP | P98170 | 1/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 5/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | EGFR | P00533 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | FYN | P06241 | 1/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.53 |
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21068070 | 1.00 | GRB2 (0.71) | GRB2SLC7A5PTGS1ALPIPKM | |
| SCHEMBL2310526 | 0.84 | SLC7A5 (0.83) | GRB2SLC7A5PTGS1ALPIPKM | |
| SCHEMBL5803441 | 0.83 | SLC7A5 (0.59) | GRB2SLC7A5PTGS1ALPIPKM | |
| SCHEMBL740393 | 0.83 | GRB2 (1.00) | GRB2SLC7A5PTGS1ALPIPKM | |
| SCHEMBL148122 | 0.82 | GRB2 (0.76) | GRB2SLC7A5PTGS1ALPIPKM | |
| SCHEMBL43861 | 0.82 | GRB2 (0.76) | GRB2SLC7A5PTGS1ALPIPKM | |
| SCHEMBL43862 | 0.82 | GRB2 (0.76) | GRB2SLC7A5PTGS1ALPIPKM | |
| SCHEMBL43852 | 0.81 | SLC7A5 (0.71) | GRB2SLC7A5PTGS1ALPIPKM | |
| SCHEMBL43851 | 0.81 | SLC7A5 (0.71) | GRB2SLC7A5PTGS1ALPIPKM | |
| SCHEMBL288375 | 0.81 | SLC7A5 (0.71) | GRB2SLC7A5PTGS1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |