Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | PPOX | P50336 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6703114 | 1.00 | MAPT (0.45) | MAPTALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL7151795 | 0.83 | RXFP1 (0.44) | MAPTALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL1808982 | 0.83 | RXFP1 (0.44) | MAPTALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL8526452 | 0.82 | ALDH1A1 (0.45) | MAPTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL39177 | 0.82 | MAPT (0.37) | MAPTALDH1A1PPOXKMT2AMAPK1 | |
| SCHEMBL5467830 | 0.82 | MAPT (0.37) | MAPTALDH1A1PPOXKMT2AMAPK1 | |
| SCHEMBL7967224 | 0.82 | ALDH1A1 (0.36) | MAPTALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL7967226 | 0.82 | ALDH1A1 (0.36) | MAPTALDH1A1SMN1; SMN2LMNAPOLB | |
| SCHEMBL7729348 | 0.80 | KMT2A (0.44) | MAPTALDH1A1LMNAPOLBKMT2A | |
| SCHEMBL7729350 | 0.80 | KMT2A (0.44) | MAPTALDH1A1LMNAPOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140243199-A1 | HERBICIDE COMBINATIONS COMPRISING SPECIFIC SULFONYLUREAS | BAYER CROPSCIENCE AG (DE) | 2014-08-28 | — | — | US | disclosed |
| US-8158558-B2 | Synergistic mixture of a mesosulfuron or iodinosulfuron ester of given formula, with another herbicide selected from a list of 23 that includes picolinafen, flucarbazone, procarbazone and cinidon-ethyl; controlling weeds in monocot crops | BAYER CROPSCIENCE GMBH (DE) | 2012-04-17 | — | — | US | disclosed |
| US-7368413-B2 | Herbicidal composition and method of using the same | NIHON NOHYAKU CO., LTD. (JP) | 2008-05-06 | — | — | US | disclosed |
| US-20050070437-A1 | Herbicide combinations comprising specific sulfonamides | BAYER CROPSCIENCE GMBH (DE) | 2005-03-31 | — | — | US | disclosed |
| WO-2002080680-A2 | SYNERGISTIC ACTIVE COMBINATIONS FOR CONTROLLING HARMFUL PLANTS | BAYER CROPSCIENCE GMBH (DE) | 2002-10-17 | — | — | WO | disclosed |
| WO-2002080679-A2 | SYNERGISTIC ACTIVE COMBINATIONS FOR CONTROLLING HARMFUL PLANTS | BAYER CROPSCIENCE GMBH (DE) | 2002-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070437-A1 | Herbicide combinations comprising specific sulfonamides | DDT, B2M, MTX2 | MAPT 4483/4885ALDH1A1 794/4885SMN1; SMN2 4360/4885 |
| US-20140243199-A1 | HERBICIDE COMBINATIONS COMPRISING SPECIFIC SULFONYLUREAS | SLC16A3, SLC16A7, MTX2 | MAPT 4740/4885ALDH1A1 651/4885SMN1; SMN2 4316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.