SCHEMBL21069060

SCHEMBL21069060

c1ccc(-c2nc(-c3ccccc3)nc(-c3ccc4c(c3)c3cc(-n5c6ccccc6c6ccccc65)ccc3n4-c3ncccn3)n2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATM Q13315 2/20 0.38
KDM4E B2RXH2 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
RAC2 P15153 1/20 0.37
RAC3 P60763 1/20 0.37
CDC42 P60953 1/20 0.37
RAC1 P63000 1/20 0.37
NPY5R Q15761 4/20 0.35
KMT2A Q03164 4/20 0.35
MAPT P10636 2/20 0.35
NPSR1 Q6W5P4 2/20 0.35
PTK2B Q14289 1/20 0.35
PTGER4 P35408 3/20 0.35
MEN1 O00255 3/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.33
ABCG2 Q9UNQ0 2/20 0.33
EDNRB P24530 1/20 0.32
EDNRA P25101 1/20 0.32
TSHR P16473 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30118242 1.00 ATM (0.38) ATMKDM4EL3MBTL1RAC2RAC3
SCHEMBL21068941 0.96 KDM4E (0.38) ATMKDM4EL3MBTL1RAC2RAC3
SCHEMBL30118220 0.94 NPY5R (0.39) ATMKDM4EL3MBTL1NPY5RKMT2A
SCHEMBL21069126 0.94 NPY5R (0.39) ATMKDM4EL3MBTL1NPY5RKMT2A
SCHEMBL21965711 0.92 ATM (0.42) ATMKDM4EL3MBTL1RAC2RAC3
SCHEMBL21965167 0.92 ATM (0.42) ATMKDM4EL3MBTL1RAC2RAC3
SCHEMBL21068957 0.92 ATM (0.42) ATMKDM4EL3MBTL1RAC2RAC3
SCHEMBL30118256 0.92 ATM (0.42) ATMKDM4EL3MBTL1RAC2RAC3
SCHEMBL21965608 0.92 ATM (0.42) ATMKDM4EL3MBTL1RAC2RAC3
SCHEMBL21163416 0.89 NPY5R (0.41) ATMKDM4EL3MBTL1NPY5RPTGER4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11575088-B2 Composition of matter for use in organic light-emitting diodes KYULUX, INC. (JP) 2023-02-07 US disclosed
US-20190198777-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES KYULUX, INC. (JP) 2019-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11575088-B2 Composition of matter for use in organic light-emitting diodes CRY2, CYBA, ALDH1A2 ATM 2253/4885KDM4E 4556/4885L3MBTL1 1186/4885
US-20190198777-A1 COMPOSITION OF MATTER FOR USE IN ORGANIC LIGHT-EMITTING DIODES CRY2, CYBA, ALDH1A2 ATM 2253/4885KDM4E 4556/4885L3MBTL1 1186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.