Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 6/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13006486 | 0.91 | LMNA (0.55) | LMNAPOLBEGFRBACE1BACE2 | |
| SCHEMBL29445397 | 0.90 | LMNA (0.53) | LMNAPOLBBACE1BACE2DHODH | |
| SCHEMBL1134823 | 0.90 | LMNA (0.53) | LMNAPOLBBACE1BACE2DHODH | |
| SCHEMBL1145119 | 0.89 | LMNA (0.53) | LMNAPOLBEGFRBACE1BACE2 | |
| SCHEMBL2793907 | 0.89 | LMNA (0.53) | LMNAPOLBEGFRBACE1BACE2 | |
| SCHEMBL19926358 | 0.89 | LMNA (0.65) | LMNAPOLBBACE1BACE2PSEN1 | |
| SCHEMBL16972277 | 0.87 | LMNA (0.63) | LMNAPOLBBACE1BACE2PSEN1 | |
| SCHEMBL973770 | 0.85 | LMNA (0.62) | LMNAPOLBEGFRDHODH | |
| SCHEMBL14578046 | 0.84 | LMNA (0.68) | LMNAPOLBSTING1NTRK1 | |
| SCHEMBL29445389 | 0.84 | LMNA (0.64) | LMNAPOLBEGFRBACE1BACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190191707-A1 | COMPOSITIONS COMPRISING BACILLUS LICHENIFORMIS AND BACILLUS SUBTILIS AND METHODS OF USE FOR CONTROLLING FUNGAL PATHOGENS | FMC CORP (US) | 2019-06-27 | — | — | US | disclosed |