Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | DHODH | Q02127 | 14/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL973104 | 0.86 | LMNA (0.56) | LMNAPOLBDHODHKLKB1 | |
| SCHEMBL28354155 | 0.86 | LMNA (0.56) | LMNAPOLBDHODHKLKB1 | |
| SCHEMBL21069191 | 0.85 | LMNA (0.64) | LMNAPOLBDHODHEGFR | |
| SCHEMBL1145119 | 0.85 | LMNA (0.53) | LMNAPOLBDHODHEGFR | |
| SCHEMBL13006486 | 0.85 | LMNA (0.55) | LMNAPOLBDHODHEGFR | |
| SCHEMBL2793907 | 0.85 | LMNA (0.53) | LMNAPOLBDHODHEGFR | |
| SCHEMBL16212719 | 0.85 | LMNA (0.53) | LMNAPOLBDHODHSMN1; SMN2EGFR | |
| SCHEMBL3354456 | 0.84 | LMNA (0.54) | LMNAPOLBDHODHSMN1; SMN2EGFR | |
| SCHEMBL972255 | 0.82 | EGFR (0.48) | DHODHSMN1; SMN2EGFR | |
| SCHEMBL971566 | 0.82 | POLB (0.66) | LMNAPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2257530-B1 | PROCESS FOR PREPARING SUBSTITUTED BIPHENYLANILIDES | BAYER CROPSCIENCE AG (DE) | 2011-10-12 | — | — | EP | disclosed |
| US-20110003999-A1 | Process for Preparing Substituted Biphenylanilides | BAYER CROPSCIENCE AG (DE) | 2011-01-06 | — | — | US | disclosed |
| EP-2093216-A1 | Process for preparing substituted biphenylanilides | Bayer CropScience AG (DE) | 2009-08-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110003999-A1 | Process for Preparing Substituted Biphenylanilides | DDT, PAH, THOP1 | LMNA 3959/4885POLB 425/4885DHODH 78/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.