Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 2/20 | 0.47 |
| ▸ | LRRK2 | Q5S007 | 4/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.42 |
| ▸ | SMARCA4 | P51532 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 4/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | CCNC | P24863 | 1/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17794955 | 0.84 | LRRK2 (0.48) | LRRK2CNR1CNR2BRD4CREBBP | |
| SCHEMBL23761239 | 0.82 | PIK3CD (0.47) | LRRK2CNR1CNR2USP30RET | |
| SCHEMBL20329621 | 0.82 | LRRK2 (0.47) | LRRK2CREBBPKDM4EUSP2ALDH1A1 | |
| SCHEMBL17806614 | 0.80 | LRRK2 (0.45) | LRRK2CNR1CNR2BRD4CREBBP | |
| SCHEMBL1814407 | 0.78 | LRRK2 (0.51) | AXLLRRK2SMARCA2SMARCA4BRD4 | |
| SCHEMBL23753798 | 0.78 | CNR1 (0.52) | LRRK2CNR1CNR2SMARCA2SMARCA4 | |
| SCHEMBL19175599 | 0.78 | LRRK2 (0.43) | LRRK2CNR1CNR2SMARCA2SMARCA4 | |
| SCHEMBL2625724 | 0.77 | ALOX5AP (0.54) | AXLLRRK2SMARCA2SMARCA4BRD4 | |
| SCHEMBL12936324 | 0.76 | ALOX5AP (0.42) | AXLLRRK2SMARCA2SMARCA4MET | |
| SCHEMBL17785770 | 0.75 | AXL (0.51) | AXLLRRK2SMARCA2SMARCA4BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190194148-A1 | TETRAZOLE-CONTAINING 1,2-CYCLOPROPANE-CARBOXAMIDES | Bayer Pharma AG (DE) | 2019-06-27 | — | — | US | disclosed |
| US-20190194148-A1 | TETRAZOLE-CONTAINING 1,2-CYCLOPROPANE-CARBOXAMIDES | Bayer Pharma AG (DE) | 2019-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190194148-A1 | TETRAZOLE-CONTAINING 1,2-CYCLOPROPANE-CARBOXAMIDES | HNMT, AANAT, CHRNA5 | AXL 4631/4885LRRK2 3113/4885CNR1 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.