Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 18/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | PTGIR | P43119 | 1/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14768424 | 0.94 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1PTGDR2CYP3A4 | |
| SCHEMBL17124779 | 0.85 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1PTGDR2CYP3A4 | |
| SCHEMBL6281909 | 0.84 | CYP1A2 (0.64) | ALDH1A1MAPK1L3MBTL1CYP3A4CYP1A2 | |
| SCHEMBL14768422 | 0.83 | HTT (0.52) | ALDH1A1MAPK1L3MBTL1PTGDR2 | |
| SCHEMBL17124773 | 0.81 | ALDH1A1 (0.63) | ALDH1A1MAPK1L3MBTL1CYP2C9TBXA2R | |
| SCHEMBL31530756 | 0.81 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1PTGDR2CYP3A4 | |
| SCHEMBL6366353 | 0.81 | NPC1 (0.59) | ALDH1A1MAPK1L3MBTL1CYP3A4CYP1A2 | |
| SCHEMBL6081043 | 0.79 | ALDH1A1 (0.64) | ALDH1A1MAPK1L3MBTL1CYP3A4CYP1A2 | |
| SCHEMBL17130188 | 0.79 | L3MBTL1 (0.47) | ALDH1A1MAPK1L3MBTL1PTGDR2CYP3A4 | |
| SCHEMBL5151754 | 0.78 | ALDH1A1 (0.58) | ALDH1A1MAPK1L3MBTL1CYP3A4CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2753599-B1 | BIPHENYL COMPOUNDS FOR USE IN TREATING MALARIA AND OTHER PARASITIC DISORDERS | MEDIZINISCHE HOCHSCHULE HANNOVER (DE) | 2019-06-05 | — | — | EP | disclosed |