⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22995436 | 0.83 | RIPK1 (0.30) | — | |
| SCHEMBL22996216 | 0.77 | — | — | |
| SCHEMBL255894 | 0.77 | HTR1A (0.35) | — | |
| SCHEMBL27348033 | 0.76 | — | — | |
| SCHEMBL24211414 | 0.75 | — | — | |
| SCHEMBL22996278 | 0.74 | — | — | |
| SCHEMBL27347672 | 0.74 | — | — | |
| SCHEMBL23815560 | 0.73 | — | — | |
| SCHEMBL21076279 | 0.70 | — | — | |
| SCHEMBL21076287 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10933139-B2 | Conjugated lipomers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-03-02 | — | — | US | disclosed |
| EP-2691443-B1 | CONJUGATED LIPOMERS AND USES THEREOF | MASSACHUSETTS INST TECHNOLOGY (US) | 2021-02-17 | — | — | EP | disclosed |
| US-20190167795-A1 | CONJUGATED LIPOMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-06-06 | — | — | US | disclosed |