Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL295997 | 0.85 | KMT2A (0.41) | ALDH1A1KDM4EUSP2SMN1; SMN2GAA | |
| SCHEMBL14856607 | 0.85 | KMT2A (0.41) | ALDH1A1KDM4EUSP2SMN1; SMN2GAA | |
| SCHEMBL19285734 | 0.85 | KMT2A (0.41) | ALDH1A1KDM4EUSP2SMN1; SMN2GAA | |
| SCHEMBL6026163 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KDM4EHSD17B10POLBGAA | |
| SCHEMBL12958952 | 0.81 | KDM4E (0.95) | ALDH1A1KDM4EUSP2GLACA12 | |
| SCHEMBL16604261 | 0.81 | KDM4E (0.95) | ALDH1A1KDM4EUSP2GLACA12 | |
| SCHEMBL371210 | 0.81 | KDM4E (0.95) | ALDH1A1KDM4EUSP2GLACA12 | |
| SCHEMBL11200585 | 0.81 | KDM4E (0.95) | ALDH1A1KDM4EUSP2GLACA12 | |
| Methyl Alcohol SCHEMBL27850055 | 0.79 | KDM4E (0.82) | ALDH1A1KDM4EUSP2GLACA12 | |
| SCHEMBL25262333 | 0.79 | KDM4E (0.90) | ALDH1A1KDM4EUSP2GLACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10933139-B2 | Conjugated lipomers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-03-02 | — | — | US | disclosed |
| US-20190167795-A1 | CONJUGATED LIPOMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190167795-A1 | CONJUGATED LIPOMERS AND USES THEREOF | EZH2, LIPC, PUF60 | ALDH1A1 1831/4885KDM4E 812/4885USP2 2138/4885 |
| US-10933139-B2 | Conjugated lipomers and uses thereof | EZH2, LIPC, PUF60 | ALDH1A1 1831/4885KDM4E 812/4885USP2 2138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.