Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21076300 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KDM4EKMT2AMEN1CYP3A4 | |
| SCHEMBL21076323 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KDM4EKMT2AMEN1CYP3A4 | |
| SCHEMBL13915394 | 1.00 | ALDH1A1 (0.46) | ALDH1A1KDM4EKMT2AMEN1CYP3A4 | |
| SCHEMBL13915448 | 0.98 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2AMEN1CYP3A4 | |
| SCHEMBL22996243 | 0.93 | ALDH1A1 (0.52) | ALDH1A1KDM4EKMT2AMEN1CYP3A4 | |
| SCHEMBL22996249 | 0.93 | ALDH1A1 (0.52) | ALDH1A1KDM4EKMT2AMEN1CYP3A4 | |
| SCHEMBL22996224 | 0.93 | ALDH1A1 (0.52) | ALDH1A1KDM4EKMT2AMEN1CYP3A4 | |
| SCHEMBL323447 | 0.93 | ALDH1A1 (0.52) | ALDH1A1KDM4EKMT2AMEN1CYP3A4 | |
| SCHEMBL22996226 | 0.88 | CXCR4 (0.44) | ALDH1A1KDM4EKMT2AMEN1CYP3A4 | |
| SCHEMBL22996258 | 0.88 | CXCR4 (0.44) | ALDH1A1KDM4EKMT2AMEN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10933139-B2 | Conjugated lipomers and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2021-03-02 | — | — | US | disclosed |
| US-20190167795-A1 | CONJUGATED LIPOMERS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190167795-A1 | CONJUGATED LIPOMERS AND USES THEREOF | EZH2, LIPC, PUF60 | ALDH1A1 1831/4885KDM4E 812/4885KMT2A 369/4885 |
| US-10933139-B2 | Conjugated lipomers and uses thereof | EZH2, LIPC, PUF60 | ALDH1A1 1831/4885KDM4E 812/4885KMT2A 369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.