SCHEMBL2108452

SCHEMBL2108452

CC=C(C(=O)Oc1cccc(Oc2ccccc2F)c1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
GCK P35557 2/20 0.45
PARP10 Q53GL7 1/20 0.44
PPARG P37231 1/20 0.42
LPAR1 Q92633 6/20 0.41
LPAR5 Q9H1C0 6/20 0.41
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
FAAH O00519 1/20 0.40
MRGPRX4 Q96LA9 1/20 0.40
AKR1C3 P42330 1/20 0.39
KMT2A Q03164 2/20 0.39
CXCL8 P10145 1/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2858454 0.80 GCK (0.44) GCKPARP10PPARGLPAR1LPAR5
SCHEMBL2107654 0.79 MEN1 (0.57) NPC1RAB9AAKR1C3KMT2AMEN1
SCHEMBL2107180 0.78 KDM4E (0.39) GCKPARP10NPC1RAB9AMRGPRX4
SCHEMBL2108453 0.78 GCK (0.41) GCKPARP10PPARGLPAR1LPAR5
SCHEMBL2108447 0.78 GCK (0.41) GCKPARP10PPARGLPAR1LPAR5
SCHEMBL27824670 0.77 AKR1C3 (0.67) GCKPARP10PPARGLPAR1LPAR5
SCHEMBL8338935 0.77 AKR1C3 (0.44) AKR1C3
SCHEMBL8343387 0.76 KMT2A (0.44) AKR1C3KMT2AMEN1ALDH1A1
SCHEMBL11305101 0.76 MEN1 (0.55) GCKPARP10PPARGLPAR1LPAR5
SCHEMBL2107666 0.75 KDM4E (0.62) LPAR1LPAR5RAB9AFAAHKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9314030-B2 Particulate wood preservative and method for producing same KOPPERS PERFORMANCE CHEMICALS INC. (US) 2016-04-19 US disclosed
US-20150056258-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME OSMOSE, INC. (US) 2015-02-26 US disclosed
US-8722198-B2 Method of preserving wood by injecting particulate wood preservative slurry OSMOSE, INC. (US) 2014-05-13 US disclosed
US-20130164362-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME OSMOSE, INC. (US) 2013-06-27 US disclosed
US-8158208-B2 Method of preserving wood by injecting particulate wood preservative slurry OSMOSE, INC. (US) 2012-04-17 US disclosed
US-20090223408-A1 Use of Sub-Micron Copper Salt Particles in Wood Preservation PHIBROWOOD, LLC (US) 2009-09-10 US disclosed
US-20090123505-A1 Particulate Wood Preservative and Method for Producing Same PHIBROWOOD, LLC (US) 2009-05-14 US disclosed
EP-1830989-A2 USE OF SUB-MICRON COPPER SALT PARTICLES IN WOOD PRESERVATION Phibro-Tech, Inc. (US) 2007-09-12 EP disclosed
WO-2006065684-A2 USE OF SUB-MICRON COPPER SALT PARTICLES IN WOOD PRESERVATION PHIBRO-TECH, INC. (US) 2006-06-22 WO disclosed
WO-2006042128-A2 TREATMENT OF WOOD WITH AN INJECTABLE WOOD PRESERVATIVE SLURRY HAVING BIOCIDAL PARTICLES PHIBRO-TECH, INC. (US) 2006-04-20 WO disclosed
US-20060062926-A1 Use of sub-micron copper salt particles in wood preservation KOPPERS INC. (F/K/A KOPPERS INDUSTRIES, INC) 2006-03-23 US disclosed
US-20050252408-A1 Particulate wood preservative and method for producing same KOPPERS PERFORMANCE CHEMICALS NEW ZEALAND LIMITED (F/K/A OSMOSE NEW ZEALAND) (NZ) 2005-11-17 US disclosed
US-5925675-A N-sulfonyliminodithio compounds useful for in plant and material protection BAYER AKTIENGESELLSCHAFT (DE) 1999-07-20 US disclosed
US-5874025-A Timber preservative containing a copper compound BAYER AKTIENGESELLSCHAFT (DE) 1999-02-23 US disclosed
US-5672617-A Medicaments containing 1-thiocarbamoyl-5-hydroxy-pyrazoles and their use as agents for combating septic shock BAYER AKTIENGESELLSCHAFT (DE) 1997-09-30 US disclosed