SCHEMBL2107666

SCHEMBL2107666

CC=C(C(=O)Oc1cccc(Oc2ccc([N+](=O)[O-])cc2)c1)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.62
FFAR1 O14842 2/20 0.57
MEN1 O00255 4/20 0.52
KMT2A Q03164 4/20 0.52
ALDH1A1 P00352 2/20 0.52
CRHBP P24387 2/20 0.49
CRHR2 Q13324 2/20 0.49
RAB9A P51151 1/20 0.48
TLR4 O00206 1/20 0.48
TLR2 O60603 1/20 0.48
FAAH O00519 1/20 0.46
MGLL Q99685 1/20 0.46
SRD5A2 P31213 1/20 0.46
LPAR1 Q92633 1/20 0.46
LPAR5 Q9H1C0 1/20 0.46
LPAR3 Q9UBY5 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.44
MAPT P10636 1/20 0.44
HTT P42858 1/20 0.44
MCL1 Q07820 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4444955 0.80 KDM4E (0.63) KDM4EFFAR1MEN1KMT2AALDH1A1
SCHEMBL2107667 0.79 KDM4E (0.56) KDM4EFFAR1MEN1KMT2AALDH1A1
SCHEMBL2107664 0.79 KDM4E (0.56) KDM4EFFAR1MEN1KMT2AALDH1A1
SCHEMBL2848086 0.78 KDM4E (0.54) KDM4EFFAR1MEN1KMT2AALDH1A1
SCHEMBL4444957 0.77 KDM4E (0.59) KDM4EFFAR1MEN1KMT2AALDH1A1
SCHEMBL177838 0.77 KDM4E (1.00) KDM4EFFAR1MEN1KMT2AALDH1A1
SCHEMBL7632953 0.76 ALDH1A1 (0.77) KDM4EFFAR1MEN1KMT2AALDH1A1
SCHEMBL27188054 0.76 ALDH1A1 (0.77) KDM4EFFAR1MEN1KMT2AALDH1A1
SCHEMBL8338935 0.76 AKR1C3 (0.44) TLR4TLR2MGLLALOX5
SCHEMBL2107654 0.76 MEN1 (0.57) MEN1KMT2AALDH1A1RAB9ATLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9314030-B2 Particulate wood preservative and method for producing same KOPPERS PERFORMANCE CHEMICALS INC. (US) 2016-04-19 US disclosed
US-20150056258-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME OSMOSE, INC. (US) 2015-02-26 US disclosed
US-8722198-B2 Method of preserving wood by injecting particulate wood preservative slurry OSMOSE, INC. (US) 2014-05-13 US disclosed
US-20130164362-A1 PARTICULATE WOOD PRESERVATIVE AND METHOD FOR PRODUCING SAME OSMOSE, INC. (US) 2013-06-27 US disclosed
US-8158208-B2 Method of preserving wood by injecting particulate wood preservative slurry OSMOSE, INC. (US) 2012-04-17 US disclosed
US-20090123505-A1 Particulate Wood Preservative and Method for Producing Same PHIBROWOOD, LLC (US) 2009-05-14 US disclosed
US-20050252408-A1 Particulate wood preservative and method for producing same KOPPERS PERFORMANCE CHEMICALS NEW ZEALAND LIMITED (F/K/A OSMOSE NEW ZEALAND) (NZ) 2005-11-17 US disclosed
US-5925675-A N-sulfonyliminodithio compounds useful for in plant and material protection BAYER AKTIENGESELLSCHAFT (DE) 1999-07-20 US disclosed
US-5874025-A Timber preservative containing a copper compound BAYER AKTIENGESELLSCHAFT (DE) 1999-02-23 US disclosed
US-5767137-A FOR INDUSTRIAL MATERIALS BAYER AKTIENGESELLSCHAFT (DE) 1998-06-16 US disclosed
US-5703103-A MICROBIOCIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-30 US disclosed
US-5672617-A Medicaments containing 1-thiocarbamoyl-5-hydroxy-pyrazoles and their use as agents for combating septic shock BAYER AKTIENGESELLSCHAFT (DE) 1997-09-30 US disclosed