Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 9/20 | 0.47 |
| ▸ | CTPS2 | Q9NRF8 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | STAT1 | P42224 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21077123 | 0.85 | CTPS1 (0.43) | CTPS1CTPS2KMT2AMEN1MAPT | |
| SCHEMBL21076857 | 0.84 | CTPS1 (0.68) | CTPS1CTPS2 | |
| SCHEMBL21076824 | 0.82 | CTPS1 (0.48) | CTPS1CTPS2KMT2AGAAMEN1 | |
| SCHEMBL21076955 | 0.82 | CTPS1 (0.47) | CTPS1CTPS2 | |
| SCHEMBL21077197 | 0.80 | CTPS1 (0.58) | CTPS1CTPS2 | |
| SCHEMBL21076987 | 0.76 | MAPK1 (0.42) | CTPS1CTPS2KMT2AGAAPDE5A | |
| SCHEMBL21076996 | 0.76 | CTPS1 (0.53) | CTPS1CTPS2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL21077100 | 0.75 | CTPS1 (0.48) | CTPS1CTPS2KMT2AGAAMEN1 | |
| SCHEMBL21076850 | 0.75 | LCK (0.39) | CTPS1CTPS2KMT2AGAAMEN1 | |
| SCHEMBL21077028 | 0.74 | CTPS1 (0.41) | CTPS1CTPS2KMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |