Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 8/20 | 0.48 |
| ▸ | CTPS2 | Q9NRF8 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | PDE1A | P54750 | 1/20 | 0.35 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.35 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21076824 | 0.85 | CTPS1 (0.48) | CTPS1CTPS2RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21077099 | 0.82 | CTPS1 (0.69) | CTPS1CTPS2 | |
| SCHEMBL21077103 | 0.82 | CTPS1 (0.40) | CTPS1CTPS2RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21077028 | 0.81 | CTPS1 (0.41) | CTPS1CTPS2RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21076987 | 0.80 | MAPK1 (0.42) | CTPS1CTPS2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL21076850 | 0.80 | LCK (0.39) | CTPS1CTPS2RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21077123 | 0.77 | CTPS1 (0.43) | CTPS1CTPS2RAB9AALDH1A1ATAD2 | |
| SCHEMBL21076996 | 0.75 | CTPS1 (0.53) | CTPS1CTPS2RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL21076854 | 0.75 | CTPS1 (0.47) | CTPS1CTPS2SMN1; SMN2ATAD2GAA | |
| SCHEMBL21077177 | 0.74 | CTPS1 (0.51) | CTPS1CTPS2NPC1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |