Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 3/20 | 0.43 |
| ▸ | CTPS2 | Q9NRF8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.37 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21076824 | 0.87 | CTPS1 (0.48) | CTPS1CTPS2MAPTHTTLMNA | |
| SCHEMBL21076854 | 0.85 | CTPS1 (0.47) | CTPS1CTPS2MAPTKMT2AMEN1 | |
| SCHEMBL21076850 | 0.83 | LCK (0.39) | CTPS1CTPS2MAPTHTTLMNA | |
| SCHEMBL21077130 | 0.83 | CTPS1 (0.64) | CTPS1CTPS2 | |
| SCHEMBL21077028 | 0.82 | CTPS1 (0.41) | CTPS1CTPS2MAPTHTTKMT2A | |
| SCHEMBL21077170 | 0.81 | CTPS1 (0.45) | CTPS1CTPS2 | |
| SCHEMBL21076996 | 0.78 | CTPS1 (0.53) | CTPS1CTPS2KMT2AMEN1RAB9A | |
| SCHEMBL21077100 | 0.77 | CTPS1 (0.48) | CTPS1CTPS2MAPTHTTLMNA | |
| SCHEMBL21076987 | 0.77 | MAPK1 (0.42) | CTPS1CTPS2MAPTHTTLMNA | |
| SCHEMBL21077121 | 0.76 | CTPS1 (0.53) | CTPS1CTPS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |