Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 16/20 | 0.48 |
| ▸ | CTPS2 | Q9NRF8 | 2/20 | 0.44 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22491687 | 0.83 | CTPS1 (0.57) | CTPS1CTPS2PIK3CG | |
| SCHEMBL21044518 | 0.78 | CTPS1 (0.72) | CTPS1CTPS2 | |
| SCHEMBL21077212 | 0.77 | CTPS1 (0.44) | CTPS1CTPS2PIK3CGABL1 | |
| SCHEMBL21077151 | 0.76 | CTPS1 (0.48) | CTPS1CTPS2PIK3CG | |
| SCHEMBL21077040 | 0.75 | CTPS1 (0.53) | CTPS1CTPS2 | |
| SCHEMBL21076967 | 0.74 | CTPS1 (0.56) | CTPS1CTPS2PIK3CG | |
| SCHEMBL21076901 | 0.74 | CTPS1 (0.45) | CTPS1CTPS2PIK3CG | |
| SCHEMBL21077176 | 0.73 | CTPS1 (0.61) | CTPS1CTPS2ABL1RORC | |
| SCHEMBL21076872 | 0.73 | CTPS1 (0.52) | CTPS1CTPS2 | |
| SCHEMBL21077076 | 0.71 | CTPS1 (0.65) | CTPS1CTPS2RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |