Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 14/20 | 0.52 |
| ▸ | CTPS2 | Q9NRF8 | 4/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21077174 | 0.87 | CTPS1 (0.44) | CTPS1CTPS2 | |
| SCHEMBL21076901 | 0.86 | CTPS1 (0.45) | CTPS1CTPS2 | |
| SCHEMBL21077036 | 0.86 | CTPS1 (0.72) | CTPS1CTPS2PIK3CD | |
| SCHEMBL21077074 | 0.85 | CTPS1 (0.60) | CTPS1CTPS2PIK3CD | |
| SCHEMBL21044464 | 0.83 | CTPS1 (0.75) | CTPS1CTPS2 | |
| SCHEMBL21077188 | 0.80 | CTPS1 (0.51) | CTPS1CTPS2 | |
| SCHEMBL21076932 | 0.80 | CTPS1 (0.52) | CTPS1CTPS2 | |
| SCHEMBL21077070 | 0.79 | CTPS1 (0.44) | CTPS1CTPS2 | |
| SCHEMBL21076924 | 0.78 | CTPS1 (0.53) | CTPS1CTPS2 | |
| SCHEMBL21077203 | 0.78 | CTPS1 (0.51) | CTPS1CTPS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |