Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTPS1 | P17812 | 9/20 | 0.45 |
| ▸ | CTPS2 | Q9NRF8 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | WNT3A | P56704 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | CDC25C | P30307 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | PDE1A | P54750 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21077165 | 0.93 | CTPS1 (0.47) | CTPS1CTPS2NPC1RAB9AWNT3A | |
| SCHEMBL21077063 | 0.91 | CTPS1 (0.49) | CTPS1CTPS2 | |
| SCHEMBL21077184 | 0.89 | CTPS1 (0.46) | CTPS1CTPS2KMT2A | |
| SCHEMBL21077153 | 0.88 | CTPS1 (0.46) | CTPS1CTPS2 | |
| SCHEMBL21077188 | 0.88 | CTPS1 (0.51) | CTPS1CTPS2 | |
| SCHEMBL21077093 | 0.86 | CTPS1 (0.55) | CTPS1CTPS2WNT3A | |
| SCHEMBL21077203 | 0.84 | CTPS1 (0.51) | CTPS1CTPS2WNT3A | |
| SCHEMBL30528776 | 0.83 | CTPS1 (0.65) | CTPS1CTPS2 | |
| SCHEMBL21044412 | 0.83 | CTPS1 (0.65) | CTPS1CTPS2 | |
| SCHEMBL21076932 | 0.83 | CTPS1 (0.52) | CTPS1CTPS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492454-A1 | COMPOUNDS | Step Pharma S.A.S. (FR) | 2019-06-05 | — | — | EP | disclosed |